Researchers review mesenchymal stem cell therapy potentialApril 18, 2018 In a review published in the Journal of Feline Medicine and Surgery, Jessica M. Quimby, DVM, Ph.D., DACVIM, Department of Veterinary Clinical Sciences at The Ohio State University, and Dori L. Borjesson, DVM, MPVM, Ph.D., Veterinary Institute for Regenerative Cures at the University of California, Davis, consider both the current and potential clinical applications of mesenchymal stem cell therapy in cats. The use of bone marrow-derived stem cells is established for the treatment of human cancer patients and, as such, veterinary applications for bone marrow- and adipose-derived stem cells are being evaluated. In their review, Drs. Quimby and Borjesson consider the emergence of this trend, as well as the current understanding of the biology/immunology of mesenchymal stem cells. Additionally, the authors analyze previous use of mesenchymal stem cells in the treatment of a number of inflammatory, degenerative, and immune-mediated diseases of cats. Traditionally, managing such conditions relies on a lifelong use of medication, with the potential for associated side effects. Often, cats do not respond to standard treatment strategies and, thus, the medication may not protect against the progression of the underlying disease. So far, applications of mesenchymal stem cell therapy in cats have produced encouraging results, including …
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