USDA no longer experimenting on cats and kittensApril 3, 2019The U.S. Department of Agriculture's (USDA's) Agricultural Research Service (ARS) says it will no longer carry out parasite experiments on cats and kittens, a practice that ultimately resulted in their being euthanized. The announcement comes weeks after U.S. congressmen Brian Mast and Jimmy Panetta introduced the Kittens in Traumatic Testing Ends Now Act of 2019. At the time, Mast said the USDA was breeding kittens for the sole purpose of feeding them raw meat laced with Toxoplasma gondii (T. gondii), a parasite considered to be a leading cause of death from foodborne illness in the U.S. ARS says cats were used in the research because they are the only host in which T. gondii can complete its life cycle and produce oocysts. The kittens were then killed even though they were healthy. In May 2018, the USDA reviewed its procedures after hearing feedback from its customers and stakeholders. ARS maintains cats have not been infected with toxoplasmosis pathogens or euthanized since September 2018. "Food safety research in ARS is of paramount importance for agriculture and the public we serve," said ARS administrator, Chavonda Jacobs-Young, PhD. "We are continually assessing our research and priorities and aligning our resources to the …
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Australian researchers discover way to halt T. gondii spreadSeptember 28, 2018According to research published in PLOS Biology, scientists in Australia have discovered a way to halt the invasion of the toxoplasmosis-causing parasite Toxoplasma gondii (T. gondii) into cells, depriving the parasite of a key factor necessary for its growth. The study found that there are two steps that allow T. gondii to take hold within the body: the parasite needs to enter a host cell; from there it replicates and spreads. "After Toxoplasma infects humans it needs to switch off the infection machinery and switch on replication," said Chris Tonkin, PhD., associate professor at the Walter and Eliza Hall Institute of Medical Research in Melbourne, who led the study. "Without the ability to do this, Toxoplasma will die and be unable to cause disease. We discovered that the gene protein kinase A (PKA) is required for this switch. Without PKA, Toxoplasma can't hold steady." The findings are an important step in getting closer to developing a vaccine to protect pregnant women from the parasite, which carries risk of miscarriage or birth defects, and may also have a link to neurological disorders such as schizophrenia, according to the study. T. gondii is transmitted by cat feces and can be acquired from …
