Canine diabetes diagnoses more common in cool tempsAugust 29, 2022Dogs living in colder climates may be more likely to be diagnosed with diabetes, the University of Pennsylvania School of Veterinary Medicine (Penn Vet) reports.
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New research for canine, human Type 1 diabetes holds promiseAugust 24, 2018Reversing Type 1 diabetes in dogs and humans without the use of daily insulin injections or pumps may become a reality, thanks to a collaboration between Purdue University and the Indiana University School of Medicine. In a preclinical study, researchers developed a mixture of collagen and pancreatic cells and engineered a delivery method that successfully reversed Type 1 diabetes within 24 hours and maintained insulin independence for 90 days. A clinical study in dogs with naturally occurring Type 1 diabetes in collaboration with Purdue's College of Veterinary Medicine is next. "We plan to account for differences from mouse to human by helping dogs first," said Clarissa Hernandez Stephens, first author on the work and a graduate researcher at Purdue's Weldon School of Biomedical Engineering. "This way, the dogs can inform us on how well the treatment might work in humans." Because diabetes in dogs and humans occurs the same, both potentially could benefit from the same cure: A new set of pancreatic cells to replace islets (clusters of cells) that aren't releasing insulin to monitor blood glucose levels. Islet transplantation isn't new, and it poses challenges: It requires multiple donors, it's invasive, and large numbers of transplanted …
NIH awards UF veterinarian five-year grant to study canine diabetesAugust 24, 2018Allison O'Kell, DVM, a small animal internal medicine specialist and clinical assistant professor at the University of Florida College of Veterinary Medicine, has received a Mentored Clinical Scientist Research Career Development Award from the National Institutes of Health in support of her studies relating to canine diabetes. The five-year grant, known as a K08, will support Dr. O'Kell's career and research project. "The overall goal of my research is to study the causes of diabetes in the dog," O'Kell said. "We hope that the work will benefit dogs with this disease, but also to help us better understand whether studying the disease in dogs may be a novel way to understand the disease in humans." The disease has been increasing in prevalence over time in both dogs and humans, emphasizing the importance of research to determine the underlying causes of the disease as well as methods for prevention and treatment, she added. O'Kell's primary mentor is Mark Atkinson, PhD, the American Diabetes Association Eminent Scholar for Diabetes Research and Jeffrey Keene Family Professor in the UF College of Medicine. Atkinson also directs the UF Diabetes Institute and has been investigating human Type 1 diabetes for …
Florida manufacturer develops rapid animal diabetes testingMarch 20, 2018Tallahassee, Fla.-based Baycom Diagnostics has developed A1Care, a cost-effective kit for monitoring and testing for both feline and canine diabetes. Much like with humans, cases of diabetes in dogs and cats have increased steadily over recent years. According to research released by Vancouver, Wash.-based Banfield Pet Hospital, instances of dog diabetes have increased from 13.1 cases per 10,000 in 2006 to 23.6 cases per 10,000 in 2015—a 79.7 percent jump in less than 10 years. While previous tests for detecting the disease in dogs and cats have been largely expensive and time consuming, A1Care is neither, the company stated. The test allows veterinarians to mail a patient's dried blood sample to Baycom's labs; the sample is analyzed and results are returned to the clinic within two weeks—all with a fee of $49 per test. "For the vets, it is super easy to use," said Gus Ray, Baycom's CEO. "Blood, information, mail, and you're done. All of the magic happens once we get the sample." Ray developed A1Care after he was hired to conduct at-home glycated hemoglobin (A1C) testing for diabetic persons. Initially, he thought the same test could be effective when testing for the disease in …
