The other ED: Ectodermal dysplasiaJuly 8, 2018From time to time, I will pull out a “dental zebra” from the archives: a case that you won’t see every day, but you’ll see it at least once in your career.
SPONSORED CONTENTBringing Light Home: How Super Pulsed Laser Therapy Enhances Pet HealingOver the past two decades, laser therapy has seen tremendous growth in veterinary practices. What was once considered an alternative therapy is now an integral part of mainstream veterinary care, particularly in rehabilitation, dental, and preventative medicine. +
Study explores predicting canine disease risk through genetic testingJune 21, 2018 Genetic testing can be used to predict if a dog is at risk for developing certain diseases, enabling preventative care for better health, reports a new study by Wisdom Health and Genoscoper Laboratories. Published in PLOS Genetics, the study, "Frequency and distribution of 152 genetic disease variants in over 100,000 mixed breed and purebred dogs," also shows fewer mixed-breed dogs than purebreds are affected by the most common disease-causing mutations tested in the study. "There has been a long-standing perception that mixed-breed dogs are less disease prone than purebred dogs," said Cindy Cole DVM, Ph.D., DACVCP, general manager at Wisdom Health. "This DNA-testing-based evidence shows that while mixed-breed dogs are in fact less likely than purebreds to develop the recessive disorders evaluated in the study, they may still be carriers." The study examined the DNA of more than 100,000 dogs (18,000 purebreds representing 330 breeds, types, and varieties, and 83,000 mixed-breed dogs) for the presence of 152 genetic disease mutations, including: Progressive retinal atrophy (multiple forms) Hyperuricosuria Collie eye anomaly Multidrug sensitivity (MDR1) von Willebrand's disease (multiple forms) Based on the 152 diseases tested: Approximately two out of 100 mixed-breed dogs are at risk of becoming affected; 40 …
Why annual screening for exposure to infected ticks is vitalJune 20, 2018It's important to remember that a single tick can transmit multiple infectious agents that may cause or contribute to serious illness, including kidney disease. And because dogs don't always show clinical signs, it can be challenging to understand the true harm of any given infection to a pet's health. This makes regularly screening of pets—including asymptomatic or seemingly healthy ones—to identify exposure to infected ticks all the more important. Here's a quick look at why regular, comprehensive screening is critical, and what veterinarians can do to help keep dogs healthy. All dogs need to be screened annually for exposure to infected ticks It's quite possible a patient could be fighting an infection without showing any signs of disease. That is why limiting screening to symptomatic pets and those known to have had a tick on them is too restrictive—it will miss infections. All dogs need to be tested, and pet owners need to be reminded that negative results are the goal in order to verify that preventive measures against ticks are working. A new study reinforces the importance of detecting exposure The study, found at idexx.com/ckdstudy, showed two key findings: 1) dogs with Ehrlichia antibodies …
Canadian researchers team up to fight canine osteosarcomaJune 14, 2018A group of researchers called the Dog Osteosarcoma Group–Biomarkers of Neoplasia (DOGBONe) at the University of Guelph in Ontario, Canada, have joined forces to determine more accurate ways of measuring bone cancer, with the main objective of identifying biomarkers to assess patients with canine osteosarcoma. The presentation of osteosarcoma in dogs is remarkably similar to that of humans, according to the Ontario Veterinary College (OVC); so much so that computers are unable to distinguish between tumor samples from each species based on gene expression patterns. These similarities make canine osteosarcoma research all the more valuable, as any progress in developing better treatments for one species means progress for the other as well. "The dogs are a model for the worst of the human disease," said Geoffrey A. Wood, DVM, Ph.D., DVSc (pathology), of the OVC's Department of Pathobiology. "Right now, the information we find out in human osteosarcoma serves as a model for the dogs. There's an opportunity to go both ways between the species, for the benefit of both." The team consists of the university's top osteosarcoma researchers from across four departments at OVC, including co-leaders Dr. Wood and Alicia Viloria-Petit, Ph.D., MSc, BSc, of the Department of …
Postoperative bleeding in greyhounds; what it may mean for deerhoundsJune 8, 2018In 2011 I wrote about research underway at The Ohio State University (OSU) to investigate the cause of excessive postoperative bleeding that occurred in many greyhounds one or two days after surgery.
How to fix oronasal fistulasMay 4, 2018This month’s column discusses the surgical approach to treatment of the most common manifestation of oronasal fistulas: those that occur in the area of the maxillary canine tooth in dogs.
Is a cure for IMHA near?May 3, 2018The image of a straight line neatly sums up the frustration of treating dogs afflicted with immune-mediated hemolytic anemia (IMHA), according to Andrew Mackin, BVMS, DVSc, FANZCVSc, DACVIM, professor and head of the Department of Clinical Sciences at Mississippi State University College of Veterinary Medicine.
MAF awards Penn $775K to test osteosarcoma immunotherapy vaccine in dogsApril 20, 2018Morris Animal Foundation (MAF) has awarded a $775,000 grant to the University of Pennsylvania to test a vaccine that could improve longevity and quality of life for dogs with osteosarcoma. The research team will conduct clinical trials to evaluate a novel immunotherapy treatment that combines a molecule expressed by cancer cells with a modified live form of Listeria monocytogenes. A pilot study demonstrated this combination elicited a powerful, targeted immune response directed against osteosarcoma cells in patients suffering from this type of cancer. "This could be an incredible breakthrough in the fight against osteosarcoma, a highly aggressive and deadly cancer," said Kelly Diehl, DVM, DACVIM (SAIM), senior scientific programs and communications adviser at MAF. "For the last 50 years, Morris Animal Foundation has been funding cancer studies, and this is one of the largest, single grants we have ever awarded. The results of the pilot study were so compelling, that we knew we had to support this research team and their progression to a clinical trial." The vaccine, created by removing harmful genes from the Listeria bacteria and then attaching markers of osteosarcoma cells, supplements standard osteosarcoma treatment of amputation and chemotherapy by attacking cancer cells that …
Merck announces inaugural Dog Flu Prevention WeekApril 18, 2018Merck Animal Health announced it has created Dog Flu Prevention Week, to be held during the third week of April annually (this year April 16-22), as a reminder to pet owners to protect their social dogs, either for the first time or for revaccination. Thousands of cases of dog flu have been confirmed across the country in the past year, and Dog Flu Prevention Week is being launched to recognize the anniversary of the discovery of the newest strain—H3N2—the party responsible for most cases. Dog Flu Prevention Week will kick off the discussion around vaccine-preventable diseases in conjunction with World Animal Vaccination Day, which is April 20. "All dogs that are social and interact with other dogs are at risk for dog flu, but the good news is that dog flu is vaccine preventable," said Kathryn Primm, DVM, co-author of the Pet Parent's Guide to Infectious Disease of Dogs. "Dogs can be protected against both strains of dog flu with a single vaccine, which is given as two doses, two to four weeks apart." Social dogs that are frequently in contact with other dogs at places like dog parks, dog day care and grooming facilities, and boarding kennels are at an increased …
Why annual screening for exposure to infected ticks is vitalApril 18, 2018It's important to remember that a single tick can transmit multiple infectious agents that may cause or contribute to serious illness, including kidney disease. And because dogs don't always show clinical signs, it can be challenging to understand the true harm of any given infection to a pet's health. This makes regularly screening pets—including asymptomatic or seemingly healthy ones—to identify exposure to infected ticks all the more important. Here's a quick look at why regular, comprehensive screening is critical, and what veterinarians can do to help keep dogs healthy. All dogs need to be screened annually for exposure to infected ticks It's quite possible a patient could be fighting an infection without showing any signs of disease. That is why limiting screening to symptomatic pets and those known to have had a tick on them is too restrictive—it will miss infections. All dogs need to be tested, and pet owners need to be reminded that negative results are the goal in order to verify that preventive measures against ticks are working. A new study reinforces the importance of detecting exposure The study, found at idexx.com/tickrisk, showed two key findings: 1) dogs with Ehrlichia antibodies …
