IsoPet canine soft-tissue sarcoma treatment delivers 'complete response'September 28, 2018Vivos Inc., a pharmaceutical company that develops minimally invasive treatments to combat cancer in humans and animals, reported that its signature product, IsoPet, was used to treat a hind-leg soft-tissue sarcoma in a Shetland sheepdog at the University of Missouri Veterinary Health Center in Columbia, Mo. The treatment of the sarcoma resulted in a "complete response," meaning tumor destruction and disappearance, together with a healthy recovery, according to veterinary oncologist Charles Maitz, DVM, PhD, DACVR-RO. Results will be presented in at the Veterinary Cancer Society's annual conference in Louisville, Ky., Oct. 17 - 20. Post-treatment imaging and dosimetry provided confirmatory data addressing questions previously raised by U.S. Food and Drug Administration review panel, including: Near-uniform placement by injection and interstitial perfusion within the tumor without vascular clearance to normal organs and tissues Very high therapeutic ratios (radiation dose to the tumor relative to normal organs) Effective, highly localized, high-dose radiotherapy, and complete absence of adverse side-effects in critical normal tissues The University of Missouri is now advertising availability of IsoPet treatment for dogs and other species, including treatment of equine sarcoids. "The successful treatment of the cat and dog subjects thus far increases the likelihood of …
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Large dogs are king according to international surveySeptember 27, 2018 According to a new international survey, dog owners say they are more satisfied owning large dogs than small dogs. The study, conducted online by RightPet starting in 2010 to 2018, surveyed dog breed reviews from 12,167 pet owners from 106 countries. Seventy-five percent of the reviews were of purebred dogs; 25 percent were of mixed breeds. The study found that both women and men are happier owning large dogs than small dogs and that men and younger people are significantly more satisfied with medium, large, and giant breeds, and less satisfied with toy and small dogs. Older people (around age 70) were found to be equally satisfied with dogs of any size, though dog owners with experience owning multiple dogs of different sizes report the greatest satisfaction with large dogs. The RightPet study found a direct correlation between dog size satisfaction and the fact that dog owners rate bigger dogs as more emotionally stable, child-safe, trainable, and less barky than small dogs. "What our study has found is that large dogs score higher in traits that are really important to most dog owners," said Brett Hodges, owner/editor at RightPet. "People don't prefer large dogs per se—they like them …
Morris Animal Foundation funds 13 wildlife studies with $850KSeptember 25, 2018Morris Animal Foundation (MAF) will extend $850,000 to fund 13 wildlife research studies. Through the new grants, the foundation is supporting scientists from Tufts University, Cornell University, and the Smithsonian Institution. The foundation's Wildlife Animal Scientific Advisory Board reviewed all submitted grant applications and selected, based on scientific merit and impact, the studies with the greatest potential to save lives, preserve health, and advance veterinary care. Wildlife studies funded for 2018 include: Understanding the Impact of Lead Poisoning in Bald Eagles Researchers will analyze multiple data sources to learn if lead continues to impact the long-term health and recovery of bald eagles. This new information will be used to help inform policy and public communication about lead exposure in bald eagles and other wildlife. Tackling Another Contagious Cancer in Tasmanian Devils Researchers will investigate a second, recently discovered, contagious cancer in Tasmanian devils, devil facial tumor 2 (DFT2). Understanding how the disease is evolving and spreading will provide important clues on how to manage this disease and other contagious cancers affecting both Tasmanian devils and dogs. Saving Endangered Frogs from Deadly Fungal Disease Researchers will look at ways to boost the immunity of …
FDA issues alert for isoxazoline class of flea, tick productsSeptember 21, 2018The U.S. Food and Drug Administration is alerting veterinarians and pet owners of the potential for neurologic adverse events in dogs and cats when treated with isoxazoline class flea and tick products, including Bravecto, Nexgard, and Simparica. Data received by the agency as part of its routine post-marketing activities indicates that some animals receiving Bravecto, Nexgard, or Simparica have experienced adverse events such as muscle tremors, ataxia, and seizures, said the FDA in a statement. Credelio, another isoxazoline class product, recently received FDA approval. These products are approved for the treatment and prevention of flea infestations, and the treatment and control of tick infestations. The FDA said it is working with manufacturers of isoxazoline products to include new label information to highlight neurologic events, as they were seen consistently across the isoxazoline class of products. These products continue to be safe and effective for the majority of animals, said the FDA, adding that it carefully reviewed studies and other data on Bravecto, Credelio, Nexgard, and Simparica prior to approval. The agency is asking the manufacturers to change product labeling in order to provide veterinarians and pet owners with the information they need to make treatment decisions …
Performance Dog recalls all frozen raw pet foodSeptember 19, 2018Bravo Packing Inc. of Carneys Point, N.J., has issued a voluntary recall of all Performance Dog products, a frozen raw pet food, due to potential Salmonella contamination. The company's recall comes after a sample of Performance Dog, collected during an FDA inspection, tested positive for Salmonella. No human or animal illnesses have been reported to date. Performance Dog generally works with the distributor Tefco, located in Brooklyn, which fills orders to brick-and-mortar retail stores or to consumers directly. Performance Dog comes frozen in 2-lb. and 5-lb. plastic sleeves. The recalled product has manufacture date code 071418. The manufacture date codes are printed on the boxes that contain the plastic sleeves, but not on the individual plastic sleeves. Therefore, if the cardboard box has been discarded, there are no unique identification numbers on the individual sleeves that allow customers to determine that they possess the recalled products. If you purchased this product since July 14 and cannot determine whether it is affected by the recall, the U.S. Food and Drug Administration recommends that you exercise caution and throw the product away. Consumers with questions should contact Bravo Packing Inc. at 856-299-1044, Monday - Friday 6 a.m. -2 p.m., and Saturday 4 …
Bayer, NeuroCycle partner to advance pet allergy treatmentsSeptember 18, 2018Bayer Animal Health and NeuroCycle Therapeutics Inc. have signed a global license agreement to advance allergy treatment options for companion animals. As part of the license agreement, Bayer will develop and commercialize novel compounds based on NeuroCycle's intellectual property. "[This] agreement underlines our strategy to combine the know-how from creative startup companies like NeuroCycle with opportunities derived from Bayer's research," said Douglas Hutchens, DVM, PhD, Bayer Animal Health's head of drug discovery, external innovation and chief veterinary officer. "It is a major milestone on our way to complementing our portfolio with novel treatment options against allergic diseases for the companion animal sector." The companies' goal is to maximize the humanitarian impact of their innovative technologies, according to Jed Hubbs, PhD, MS, CEO of NeuroCycle Therapeutics.
Cytopoint now approved to treat canine allergic dermatitisSeptember 17, 2018Zoetis announced the U.S. Department of Agriculture (USDA) has granted an expanded indication for Cytopoint, a monoclonal antibody (mAb) therapy for the treatment of allergic dermatitis in dogs. Administered every four to eight weeks, one injection of Cytopoint works by targeting and neutralizing interleukin-31 (IL-31), a key protein involved in triggering itch in dogs, offering both convenience and sustained efficacy, according to Zoetis. "This approval gives veterinarians much-needed flexibility for personalized treatment of allergic and atopic dermatitis in dogs with two therapeutic approaches—the injectable Cytopoint and the oral tablet Apoquel," said Thomas P. Lewis II, DVM, DACVD, of Dermatology for Animals in Gilbert, Ariz. "Allergic dogs and their owners have a variety of needs, and these medications from Zoetis can bring fast and long-lasting relief to my canine allergy patients, as well as bring peace of mind to their owners." Apoquel (oclacitinib tablet) is formulated to start relieving itch within four hours and provides veterinarians with the flexibility to start and stop itch control, according to Zoetis. Cytopoint begins to relieve itch within 24 hours and provides sustained itch relief for four to eight weeks, giving the skin time to heal, the company stated. They may …
Probiotic subject of two new clinical trials in domestic dogsSeptember 14, 2018ExeGi Pharma announced two new clinical partnerships with the University of Georgia College of Veterinary Medicine and the University of Tennessee to study the company's Visbiome Vet probiotic in domestic dogs. Both studies will evaluate the probiotic's effectiveness in managing canine gastrointestinal disorders. Visbiome Vet is an eight-strain probiotic compound with a high concentration of beneficial bacteria (112.5 billion bacteria per dose); the product has been the subject of four controlled clinical trials thus far. The University of Georgia will research effects of the product on diarrhea levels in dogs postsurgery. The placebo-controlled study will evaluate the incidence and severity of diarrhea, as well as changes to the canine microbiome. The second study, conducted by the University of Tennessee Institute of Agriculture, will evaluate reduction of severe diarrhea in canine acute gastroenteritis after consumption of Visbiome Vet. This placebo-controlled study will compare the safety and efficacy of Visbiome Vet to dietary changes with a specifically formulated medical diet, or antibiotics (metronidazole). "Gastrointestinal disorders are a common cause for pet owners to seek the medical care of a veterinarian," said Al Jergens, DVM, PhD. "Modulating the gut microbiome with high potency probiotics may prove to be a …
Thirteen dogs win Walkin' Pets calendar contest supporting disabled petsSeptember 13, 2018The 2019 Walkin' Pets worldwide calendar contest has announced 13 winners from around the world. This year, the winning dogs hail from eight countries: Thailand, Brazil, Germany, England, United States, Mexico, Italy, and Wales. The champions were selected by popular vote on the Walkin' Pets Facebook page and were announced through a video by the company. The winning dogs range in age from 1 to 11 and are of all sizes and breeds, including a dachshund, a German shepherd, a Siberian husky, French bulldog, and more. Each year, the contest features pets using Walkin' Wheels wheelchairs to help raise awareness of options for disabled pets with mobility challenges. The 2019 calendar is available for pre-order at (888) 253-0777. All proceeds from calendar sales go to the Handicapped Pets Foundation.
California to test pilot program for injured police dogsSeptember 13, 2018California Governor Jerry Brown signed Assembly Bill 1776 on Sept. 6, establishing a pilot program that would authorize medical technicians to provide emergency, ground-based transportation to a veterinary facility for police dogs injured in the line of duty. This bill would authorize the County of San Bernardino to work with the Inland Counties Emergency Medical Agency to conduct a pilot project starting Jan. 1, 2019, in which they collect specified data about the results and submit a report to the Legislature by Jan. 1, 2022. As an exception, there must be no person requiring medical attention or transportation at the scene when the request is made, and the ambulance must have a policy permitting the transportation of an injured police dog. The canine handler must accompany the dog and remain in full control during transport. Additionally, the canine handler remains responsible for any first aid given to the injured police dog during transport.
